I think we can break down the trials into the following with respect to cardioprotection and FTO inhibition:
1. Are the patients getting positive outcome (cancer/ symptom reduction) from the treatment and are the side effects as expected or below known adverse events.
2. Is that due to cardio protection and/ or FTO inhibition? How can we prove it?
3. Is it significant enough?
4. Are there any doubts in terms of safety, efficacy or the contribution of Bisantrene to the patient outcomes?
Anything else?
I think we can break down the trials into the following with...
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