Not to mention that the one patient who did sadly pass, had the...

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Grainofsand

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17/05/24

17:41

Post #: 73884633
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Originally posted by adreamer: ↑

Let's just remember, the scientific side has not been significantly impacted by all that is happening a the board level
The drug seems to be doing something that NOTHING else has or can - it is keeping these generous people alive longer.

10 patients have joined and continue on the OLE trial
1 patient to transition from the compassionate use program to the OLE trail within the next 2 weeks
1 patient who completed the Phase 1 / 2 trial sadly passed away whilst being on compassionate use

In the image below it shows us that.

3 patients have a slightly better than 60% to 50% chance of being alive today
3 patients have a slightly less than 50% to 37.5% chance of being alive today
1 patient has around a 30% chance of being alive today
1 patient has around a 26% chance of being alive today
4 patients are less than 25% chance of being alive today

We have only lost 1 patient to date! That person was not on the trial and we don't and won't know the circumstances.

11 out of 12 alive with odds like the above is a bloody good sign that we have something very special.

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Not to mention that the one patient who did sadly pass, had the most aggressive form of MND - Bulbars. Life expectancy for Bulbars MND sufferers is on average15 months from the onset of symptoms. This patient lived to 21 months since disease onset - a 40% increase on life expectancy above the average! It is open to speculation if they might have benefited even more if they had started MPL earlier after symptom onset.
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0 Great analysis

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